4 PC FRAMED HISTORICAL SURGEON AND SCIENTIST SIGNATURES & PICS: Comprising 1 Alexis Carrel (1873-1944) hand-written letter dated the year he won the Nobel Prize (1912), also known as the father of vascular surgery, 1 John Abernathy (1764-1831) engraving & signature dated 1814, 1 Dr. Theodor Billroth (1829-1894) engraving & signature dated 1881, Known as the father of modern abdominal surgery. 1 Thomas Henry Huxley (1825-1895) photo & signature, who was a biologist and advocate for Charles Darwin's theory of evolution. Largest Approx. 18'' h x 21.5'' w.